Medical Science about Cognition and Aging

What is Cognition?

Cognition can be defined as the activities taking place in the brain. In order to carry out all activities which includes memory retention, information storage, thought process and speech recognition, the brain needs at least 20% of the oxygen from the body. This shows how much the brain is a hungry organ. Since the brain is also a part of the Central Nervous System (CNS), it is obvious that we depend on this organ for the movement of limbs. Nerves and the spinal cord are also included in the CNS.

How is Cognition related to aging?

The cerebral blood flow from the body’s veins and arteries along with the 20% oxygen is crucial for the proper functioning of the brain. However, this percentage decreases with age as the blood vessels do not have the same flexibility to deliver blood. Moreover, the production of oxygen is reduced in the body by which the brain starts to get fatigued and the activities are slowed down. If the brain cannot function efficiently, major processes will not take place like before.

This will result in a neurological decline. Certain mental disorders such as Alzheimer’s, Parkinson’s and hypertension are common with neurological decline. The person will start to become forgetful and will not be able to form coherent thoughts and words easily. The overall coordination between the body parts will be impaired as well.

Can Cognition be Restored?

After a vast array of research, it has been understood that the cognitive abilities can be improved and even restored as well. The molecule which achieves this successfully is no other than the Nicotinamide Mononucleotide. It is no wonder that the best anti-aging NMN supplement dramatically boosts cognition. This is done by reducing the oxidative stress of the mitochondria in the brain cells.

Mitochondria is the powerhouse present in every cell. When attention to the mitochondria is given, the cognitive abilities are automatically increased.

Moreover, old age is characterized by the low levels of NAD+. NAD is the precursor to Nicotinamide Mononucleotide which is why it is important for the molecule. For the cognition, it is crucial to have an abundant amount of Nicotinamide Adenine Dinucleotide because it gives power to the mitochondria

especially the ones present in the brain. If the levels of NAD are decreased, all the cellular activities and cellular energy will collapse because no power given to mitochondria means that the cell’s powerhouse is weakened. Resultantly, the cognitive abilities will get impaired. Therefore, scientists have been trying to make NAD+ repletion therapies so that the levels of the molecule can be increased.

An experiment was held on laboratory mice which were regular doses of NMN to determine its influence on the cognition. After giving NMN to the mice for a few weeks, positive results were shown which are summarized below.

  1. With the increase of the cerebral blood flow, maximum nutrients and oxygen began to deliver to the brain.
  2. The toxic metabolites which harmed the cognitive abilities were washed away.
  3. Mechanism of the brain and the blood vessels were strengthened.

This discovery is a ray of hope for people suffering from neurological decline and age-related poor cognition.

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